Site-specific analysis of ribosomal 2'O-methylation by quantitative reverse transcription PCR under low deoxynucleotide triphosphate concentrations

Barros-Silva, D; Tsui, JH; Jerónimo, C; Jenster, G; Martens-Uzunova, ES

Martens-Uzunova, ES (通讯作者),Univ Med Ctr Rotterdam, Erasmus MC Canc Inst, Dept Urol, Be 331,POB 2040, NL-3000 CA Rotterdam, Netherlands.

BIOTECHNIQUES, 2023; 74 (5): 225

Abstract

Ribose 2'O-methylation (Nm, ribomethylation) is the most abundant RNA modification present in rRNA. It has been shown that alterations in ribo-somal 2......

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