PRMT1 loss sensitizes cells to PRMT5 inhibition

Gao, GZ; Zhang, L; Villarreal, OD; He, W; Su, D; Bedford, E; Moh, P; Shen, JJ; Shi, XB; Bedford, MT; Xu, H

Bedford, MT; Xu, H (reprint author), Univ Texas MD Anderson Canc Ctr, Dept Epigenet & Mol Carcinogenesis, Smithville, TX 78957 USA.

NUCLEIC ACIDS RESEARCH, 2019; 47 (10): 5038

Abstract

PRMT5 is an arginine methyltransferase that accounts for the vast majority of the symmetric methylation in cells. PRMT5 exerts its function when compl......

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