Preventing chemotherapy-induced myelosuppression by repurposing the FLT3 inhibitor quizartinib

Taylor, SJ; Duyvestyn, JM; Dagger, SA; Dishington, EJ; Rinaldi, CA; Dovey, OM; Vassiliou, GS; Grove, CS; Langdon, WY

Langdon, WY (reprint author), Univ Western Australia, Sch Pathol & Lab Med, Crawley, WA 6009, Australia.

SCIENCE TRANSLATIONAL MEDICINE, 2017; 9 (402):

Abstract

We describe an approach to inhibit chemotherapy-induced myelosuppression. We found that short-term exposure of mice to the FLT3 inhibitor quizartinib ......

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