The onset of PI3K-related vascular malformations occurs during angiogenesis and is prevented by the AKT inhibitor miransertib

Kobialka, P; Sabata, H; Vilalta, O; Gouveia, L; Angulo-Urarte, A; Muixi, L; Zanoncello, J; Munoz-Aznar, O; Olaciregui, NG; Fanlo, L; Esteve-Codina, A; Lavarino, C; Javierre, BM; Celis, V; Rovira, C; Lopez-Fernandez, S; Baselga, E; Mora, J; Castillo, SD; Graupera, M

Castillo, SD; Graupera, M (通讯作者),Josep Carreras Leukaemia Res Inst, Endothelial Pathobiol & Microenvironm, Barcelona, Spain.;Graupera, M (通讯作者),Inst Salud Carlos III, CIBERONC, Madrid, Spain.

EMBO MOLECULAR MEDICINE, 2022; 14 (7):

Abstract

Low-flow vascular malformations are congenital overgrowths composed of abnormal blood vessels potentially causing pain, bleeding and obstruction of di......

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