Cantharidin Inhibits Anti-Apoptotic Bcl-2 Family Proteins and Induces Apoptosis in Human Osteosarcoma Cell Lines MG-63 and MNNG/HOS via Mitochondria-Dependent Pathway

Feng, SM; Zhu, J; Xia, KS; Yu, W; Wang, YT; Wang, JJ; Li, FC; Yang, ZM; Yang, XB; Liu, B; Tao, HM; Liang, CZ

Tao, HM; Liang, CZ (reprint author), Zhejiang Univ, Sch Med, Dept Orthoped, Affiliated Hosp 2, Hangzhou, Zhejiang, Peoples R China.; Tao, HM; Liang, CZ (reprint author), Zhejiang Univ, Orthoped Res Inst, Hangzhou, Zhejiang, Peoples R China.

MEDICAL SCIENCE MONITOR, 2018; 24 (): 6742

Abstract

Background: Cantharidin (CTD) is one of the major active ingredients of blister beetles and has significant antitumor activity in many cancer cell lin......

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