Purification of linearized template plasmid DNA decreases double-stranded RNA formation during IVT reaction

Martínez, J; Lampaya, V; Larraga, A; Magallón, H; Casabona, D

Casabona, D (通讯作者)，Certest Biotec, RNA Synth & Dev Dept, Certest Pharm, Zaragoza, Spain.

FRONTIERS IN MOLECULAR BIOSCIENCES, 2023; 10 ():

Abstract

After the COVID-19 pandemic, messenger RNA (mRNA) has revolutionized traditional vaccine manufacturing. With the increasing number of RNA-based therap......

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