Apoptotic extracellular vesicles alleviate Pg-LPS induced inflammation of macrophages via AMPK/SIRT1/NF-kappa B pathway and inhibit adjacent osteoclast formation

Ye, QY; Xu, HK; Liu, SY; Li, ZH; Zhou, J; Ding, F; Zhang, XG; Wang, YZ; Jin, Y; Wang, QT

Wang, QT (通讯作者),Air Force Med Univ, Sch Stomatol, Dept Periodontol, Xian 710032, Shaanxi, Peoples R China.;Jin, Y (通讯作者),Air Force Med Univ, Sch Stomatol, Ctr Tissue Engn, Xian 710032, Shaanxi, Peoples R China.

JOURNAL OF PERIODONTOLOGY, 2022; 93 (11): 1738

Abstract

Background: Periodontitis is caused by the imbalance of anti-bacteria immune response and excessive inflammation whereas macrophages play an important......

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