Dabrafenib plus Trametinib in Pediatric Glioma with BRAF V600 Mutations

Bouffet, E; Hansford, JR; Garre, ML; Hara, J; Plant-Fox, A; Aerts, I; Locatelli, F; van der Lugt, J; Papusha, L; Sahm, F; Tabori, U; Cohen, KJ; Packer, RJ; Witt, O; Sandalic, L; da Silva, ABP; Russo, M; Hargrave, DR

Bouffet, E (通讯作者)，Hosp Sick Children, 555 Univ Ave, Toronto, ON M5G 1X8, Canada.

NEW ENGLAND JOURNAL OF MEDICINE, 2023; 389 (12): 1108

Abstract

BACKGROUND Detection of the BRAF V600E mutation in pediatric low-grade glioma has been associated with a lower response to standard chemotherapy. In p......

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