Bacterial lipopolysaccharide and antimicrobial LL-37 enhance ICAM-1 expression and NF-kappa B p65 phosphorylation in senescent endothelial cells

Suzuki, K; Ohkuma, M; Nagaoka, I

Nagaoka, I (reprint author), Juntendo Univ, Grad Sch Med, Dept Host Def & Biochem Res, Bunkyo Ku, 2-1-1 Hongo, Tokyo 1138421, Japan.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2019; 44 (4): 1187

Abstract

Cellular senescence is associated with the induction of a proinflammatory phenotype. Notably, senescent endothelial cells are detected at the sites of......

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