Role of Alanine Racemase Mutations in Mycobacterium tuberculosis D-Cycloserine Resistance

Nakatani, Y; Opel-Reading, HK; Merker, M; Machado, D; Andres, S; Kumar, SS; Moradigaravand, D; Coll, F; Perdigao, J; Portugal, I; Schon, T; Nair, D; Devi, KRU; Kohl, TA; Beckert, P; Clark, TG; Maphalala, G; Khumalo, D; Diel, R; Klaos, K; Aung, HL; Co

Krause, KL (reprint author), Univ Auckland, Maurice Wilkins Ctr Mol Biodiscovery, Auckland, New Zealand.; Krause, KL (reprint author), Univ Otago, Otago Sch Med Sci, Dept Biochem, Dunedin, New Zealand.; Koser, CU (reprint author), Univ Cambridge, Dept Gen

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2017; 61 (12):

Abstract

A screening of more than 1,500 drug-resistant strains of Mycobacterium tuberculosis revealed evolutionary patterns characteristic of positive selectio......

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