Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors

AlDubayan, SH; Pyle, LC; Gamulin, M; Kulis, T; Moore, ND; Taylor-Weiner, A; Hamid, AA; Reardon, B; Wubbenhorst, B; Godse, R; Vaughn, DJ; Jacobs, LA; Meien, S; Grgic, M; Kastelan, Z; Markt, SC; Damrauer, SM; Rader, DJ; Kember, RL; Loud, JT; Kanetsky,

Van Allen, EM (reprint author), Harvard Med Sch, Dana Farber Canc Inst, Dept Med Oncol, 360 Longwood Ave,LC 9326, Boston, MA 02215 USA.

JAMA ONCOLOGY, 2019; 5 (4): 514

Abstract

IMPORTANCE Approximately 50% of the risk for the development of testicular germ cell tumors (TGCTs) is estimated to be heritable, but no mendelian TGC......

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