Differential compartmentalization of BMP4/NOGGIN requires NOGGIN trans-epithelial transport

Phan-Everson, T; Etoc, F; Li, S; Khodursky, S; Yoney, A; Brivanlou, AH; Siggia, ED

Brivanlou, AH (corresponding author), Rockefeller Univ, Lab Stem Cell Biol & Mol Embryol, New York, NY 10065 USA.; Siggia, ED (corresponding author), Rockefeller Univ, Ctr Studies Phys & Biol, New York, NY 10065 USA.

DEVELOPMENTAL CELL, 2021; 56 (13): 1930

Abstract

Using self-organizing human models of gastrulation, we previously showed that (1) BMP4 initiates the cascade of events leading to gastrulation, (2) BM......

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