Palmitoylation couples the kinases DLK and JNK3 to facilitate prodegenerative axon-to-soma signaling

Niu, JW; Holland, SM; Ketschek, A; Collura, KM; Hesketh, NL; Hayashi, T; Gallo, G; Thomas, GM

Thomas, GM (通讯作者),Temple Univ, Shriners Hosp, Lewis Katz Sch Med, Pediat Res Ctr,Ctr Neurorehabil & Neural Repair, 3500 N Broad St, Philadelphia, PA 19140 USA.;Thomas, GM (通讯作者),Temple Univ, Dept Neural Sci, Lewis Katz Sch Med, 3500 N Broad St, Philadelphia, PA 19140 USA.

SCIENCE SIGNALING, 2022; 15 (727):

Abstract

Dual leucine-zipper kinase (DLK; a MAP3K) mediates neuronal responses to diverse injuries and insults through the c-Jun N-terminal kinase (JNK) family......

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