Low-Dose vs Standard-Dose Alteplase in Acute Lacunar Ischemic Stroke The ENCHANTED Trial

Zhou, ZE; Delcourt, C; Xia, C; Yoshimura, S; Carcel, C; Torii-Yoshimura, T; You, SJ; Malavera, A; Chen, XY; Hackett, ML; Woodward, M; Chalmers, J; Xu, JR; Robinson, TG; Parsons, MW; Demchuk, AM; Lindley, RI; Mair, G; Wardlaw, JM; Anderson, CS

Anderson, CS (corresponding author), Univ New South Wales Sydney, George Inst Global Hlth, Fac Med, Sydney, NSW, Australia.; Anderson, CS (corresponding author), Royal Prince Alfred Hosp, Sydney Hlth Partners, Dept Neurol, Camperdown, NSW, Australia.; Anderson, CS (corresponding author), Peking Univ, Hlth Sci Ctr, George Inst China, Beijing, Peoples R China.

NEUROLOGY, 2021; 96 (11): E1512

Abstract

Objective To determine any differential efficacy and safety of low- vs standard-dose IV alteplase for lacunar vs nonlacunar acute ischemic stroke (AIS......

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