HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis

Sun, YQ; Zhou, B; Mao, FB; Xu, J; Miao, HZ; Zou, ZH; Khoa, LTP; Jang, Y; Cai, S; Witkin, M; Koche, R; Ge, K; Dressler, GR; Levine, RL; Armstrong, SA; Dou, YL; Hess, JL

Dou, YL (reprint author), Univ Michigan, Sch Med, Dept Pathol, Ann Arbor, MI 48109 USA.; Dou, YL (reprint author), Univ Michigan, Sch Med, Dept Biol Chem, Ann Arbor, MI 48109 USA.; Hess, JL (reprint author), Indiana Univ Sch Med, Dept Pathol & Lab Med, In

CANCER CELL, 2018; 34 (4): 643

Abstract

Aberrant expression of HOXA9 is a prominent feature of acute leukemia driven by diverse oncogenes. Here we show that HOXA9 overexpression in myeloid a......

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