Delta Np73 overexpression promotes resistance to apoptosis but does not cooperate with PML/RARA in the induction of an APL-leukemic phenotype

Lucena-Araujo, AR; Coelho-Silva, JL; Pereira-Martins, DA; Thome, C; Scheucher, PS; Lange, AP; Paiva, HH; Hemmelgarn, BT; Morais-Sobral, MC; Azevedo, EA; Franca-Neto, PL; Franca, RF; Silva, CL; Krause, A; Rego, EM

Lucena-Araujo, AR (reprint author), Med Sch Ribeirao Preto, Dept Internal Med, Ribeirao Preto, Brazil.; Lucena-Araujo, AR (reprint author), Univ Fed Pernambuco, Dept Genet, Recife, PE, Brazil.

ONCOTARGET, 2017; 8 (5): 8475

Abstract

Here, we evaluated whether the overexpression of transcriptionally inactive Delta Np73 cooperates with PML/RARA fusion protein in the induction of an ......

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