Electroacupuncture Attenuates Morphine Tolerance in Rats with Bone Cancer Pain by Inhibiting PI3K/Akt/JNK1/2 Signaling Pathway in the Spinal Dorsal Horn

Jiang, B; Zhong, XM; Fang, JF; Zhang, AJ; Wang, W; Liang, Y; Fang, JQ; Chen, F; Du, JY

Chen, F (corresponding author), Jiaxing Univ, First Hosp Jiaxing, Affiliated Hosp, 1882 South Zhonghuan Rd, Jiaxing 314001, Zhejiang, Peoples R China.; Du, JY (corresponding author), Zhejiang Chinese Med Univ, Dept Neurobiol & Acupuncture Res, Third Clin Med Coll, Key Lab Acupuncture & Neurol Zhejiang Prov, 548 Binwen Rd, Hangzhou 310053, Zhejiang, Peoples R China.

INTEGRATIVE CANCER THERAPIES, 2021; 20 ():

Abstract

Purpose: Morphine is often used for the treatment of moderate and severe cancer pain, but long-term use can lead to morphine tolerance. Methods for ef......

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