An albumin scaffold grafted with an alpha-helical motif delivers therapeutic payloads by modular coiled-coil assembly

Rahimizadeh, P; Lee, JE; Lee, DH; Lim, SI

Lim, SI (通讯作者),Pukyong Natl Univ, Dept Chem Engn, 45 Yongso Ro, Busan 48513, South Korea.;Lee, DH (通讯作者),Gangneung Wonju Natl Univ, Dept Marine Food Sci & Technol, Kangnung 25457, South Korea.;Lee, DH (通讯作者),Nbios Inc, Kangnung 25457, South Korea.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022; 205 (): 376

Abstract

A short in vivo half-life of protein-based therapeutics often restricts successful clinical translation despite their promising efficacy in vitro. As ......

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