Trypanosoma brucei RAP1 maintains telomere and subtelomere integrity by suppressing TERRA and telomeric RNA: DNA hybrids

Nanavaty, V; Sandhu, R; Jehi, SE; Pandya, UM; Li, BB

Li, BB (reprint author), Cleveland State Univ, Ctr Gene Regulat Hlth & Dis, Dept Biol Geol & Environm Sci, 2121 Euclid Ave, Cleveland, OH 44115 USA.; Li, BB (reprint author), Rockefeller Univ, 1230 York Ave, New York, NY 10065 USA.; Li, BB (reprint author

NUCLEIC ACIDS RESEARCH, 2017; 45 (10): 5785

Abstract

Trypanosoma brucei causes human African trypanosomiasis and regularly switches its major surface antigen, VSG, thereby evading the host's immune respo......

Full Text Link