ATR Inhibition Induces CDK1-SPOP Signaling and Enhances Anti-PD-L1 Cytotoxicity in Prostate Cancer

Tang, Z; Pilie, PG; Geng, CD; Manyam, GC; Yang, G; Park, S; Wang, DQ; Peng, S; Wu, C; Peng, G; Yap, TA; Corn, PG; Broom, BM; Thompson, TC

Thompson, TC (corresponding author), Univ Texas MD Anderson Canc Ctr, 1515 Holcombe Blvd,Unit 18-3, Houston, TX 77030 USA.

CLINICAL CANCER RESEARCH, 2021; 27 (17): 4898

Abstract

Purpose Despite significant benefit for other cancer subtypes, immune checkpoint blockade (ICB) therapy has not yet been shown to significantly improv......

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