A novel fusion protein scaffold 18/12/TxM activates the IL-12, IL-15, and IL-18 receptors to induce human memory-like natural killer cells

Cubitt, CC; McClain, E; Becker-Hapak, M; Foltz, JA; Wong, P; Wagner, JA; Neal, CC; Marin, ND; Marsala, L; Foster, M; Schappe, T; Soon-Shiong, P; Lee, J; Berrien-Elliott, MM; Fehniger, TA

Fehniger, TA (通讯作者)，Washington Univ, Sch Med, 425 South Euclid Ave,Campus Box 8007, St Louis, MO 63110 USA.

MOLECULAR THERAPY-ONCOLYTICS, 2022; 24 (): 585

Abstract

Natural killer (NK) cells are cytotoxic innate lymphoid cells that are emerging as a cellular immunotherapy for various ma-lignancies. NK cells are pa......

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