TGF beta/SMAD/microRNA-486-3p Signaling Axis Mediates Keratin 17 Expression and Keratinocyte Hyperproliferation in Psoriasis

Jiang, M; Sun, ZB; Dang, EL; Li, B; Fang, H; Li, JQ; Gao, L; Zhang, KM; Wang, G

Wang, G (reprint author), Fourth Mil Med Univ, Xijing Hosp, Dept Dermatol, 127 Changlexi Rd, Xian 710032, Shaanxi, Peoples R China.

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2017; 137 (10): 2177

Abstract

Keratin 17 (K17) is strongly expressed in psoriatic lesions but not healthy skin, and plays a crucial role in disease pathogenesis. The mechanism of a......

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