IL-36 Signaling Facilitates Activation of the NLRP3 Inflammasome and IL-23/IL-17 Axis in Renal Inflammation and Fibrosis

Chi, HH; Hua, KF; Lin, YC; Chu, CL; Hsieh, CY; Hsu, YJ; Ka, SM; Tsai, YL; Liu, FC; Chen, A

Ka, SM (reprint author), Natl Def Med Ctr, Grad Inst Aerosp & Undersea Med, 161,Sect 6,Min Quan East Rd, Taipei, Taiwan.; Chen, A (reprint author), Triserv Gen Hosp, Natl Def Med Ctr, Dept Pathol, 325,Sect 2,Cheng Gung Rd, Taipei, Taiwan.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2017; 28 (7): 2022

Abstract

IL-36 cytokines are proinflammatory and have an important role in innate and adaptive immunity, but the role of IL-36 signaling in renal tubulointerst......

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