NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers

Ong, CEB; Patchett, AL; Darby, JM; Chen, JY; Liu, GS; Lyons, AB; Woods, GM; Flies, AS

Flies, AS (corresponding author), Univ Tasmania, Coll Hlth & Med, Menzies Inst Med Res, Private Bag 23, Hobart, Tas 7000, Australia.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021; 147 (7): 1973

Abstract

Purpose Downregulation of MHC class I (MHC-I) is a common immune evasion strategy of many cancers. Similarly, two allogeneic clonal transmissible canc......

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