Effective Perturbations of the Amplitude, Gating, and Hysteresis of I-K(DR) Caused by PT-2385, an HIF-2 alpha Inhibitor

Hsiao, HT; Lu, GL; Liu, YC; Wu, SN

Liu, YC (corresponding author), Natl Cheng Kung Univ, Natl Cheng Kung Univ Hosp, Coll Med, Dept Anesthesiol, Tainan 70403, Taiwan.; Liu, YC (corresponding author), Kaohsiung Med Univ, Coll Med, Sch Postbaccalaureate, Dept Anesthesiol, Kaohsiung 80708, Taiwan.; Wu, SN (corresponding author), Natl Cheng Kung Univ, Coll Med, Inst Basic Med Sci, Tainan 70101, Taiwan.; Wu, SN (corresponding author), Natl Cheng Kung Univ, Coll Med, Dept Physiol, Tainan 70101, Taiwan.

MEMBRANES, 2021; 11 (8):

Abstract

PT-2385 is currently regarded as a potent and selective inhibitor of hypoxia-inducible factor-2 alpha (HIF-2 alpha), with potential antineoplastic act......

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