Hearing of Otof-deficient mice restored by trans-splicing of N- and C-terminal otoferlin

Tang, HH; Wang, H; Wang, SY; Hu, SW; Lv, J; Xun, MZ; Gao, KY; Wang, F; Chen, YX; Wang, DQ; Wang, WQ; Li, HW; Shu, YL

Wang, WQ; Li, HW; Shu, YL (通讯作者)，Fudan Univ, ENT Inst, Shanghai 200031, Peoples R China.;Wang, WQ; Li, HW; Shu, YL (通讯作者)，Fudan Univ, Dept Otorhinolaryngol, Eye & ENT Hosp, State Key Lab Med Neurobiol, Shanghai 200031, Peoples R China.;Wang, WQ; Li, HW; Shu, YL (通讯作者)，Fudan Univ, MOE Frontiers Ctr Brain Sci, Shanghai 200031, Peoples R China.;Wang, WQ; Li, HW; Shu, YL (通讯作者)，Fudan Univ, Inst Biomed Sci, Shanghai 200032, Peoples R China.;Wang, WQ; Li, HW; Shu, YL (通讯作者)，Fudan Univ, NHC Key Lab Hearing Med, Shanghai 200032, Peoples R China.

HUMAN GENETICS, 2023; 142 (2): 289

Abstract

Mutations to the OTOF gene are among the most common reasons for auditory neuropathy. Although cochlear implants are often effective in restoring soun......

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