Antimalarial activity and sensitization of chrysosplenetin against artemisinin-resistant genotype Plasmodium berghei K173 potentially via dual-mechanism of maintaining host P-glycoprotein homeostasis mediated by NF-κB p52 or PXR/CAR signaling pathways and regulating heme/haemozoin metabolism

Wang, LR; Ji, HY; Ni, SH; Xu, JJ; Zhang, YY; Zhao, XS; Wu, XL; Tian, JX; Chen, J

Chen, J (通讯作者)，Yangzhou Univ, Inst Translat Med, Med Coll, 136 Jiangyang Middle Rd, Yangzhou 225009, Jiangsu, Peoples R China.

PHYTOTHERAPY RESEARCH, 2023; 37 (7): 2939

Abstract

This study investigated antimalarial efficacy and sensitization of chrysosplenetin against artemisinin-resistant Plasmodium berghei K173 and potential......

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