JunD, not c-Jun, is the AP-1 transcription factor required for Ras-induced lung cancer-MedSci.cn

JunD, not c-Jun, is the AP-1 transcription factor required for Ras-induced lung cancer

Ruiz, EJ; Lan, LX; Diefenbacher, ME; Riising, EM; Da Costa, C; Chakraborty, A; Hoeck, JD; Spencer-Dene, B; Kelly, G; David, JP; Nye, E; Downward, J; Behrens, A

Behrens, A (corresponding author), Inst Canc Res, Canc Stem Cell Lab, 237 Fulham Rd, London SW3 6JB, England.

JCI INSIGHT, 2021; 6 (13):

Abstract

The AP-1 transcription factor c-Jun is required for Ras-driven tumorigenesis in many tissues and is considered as a classical proto-oncogene. To deter......

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