Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1

Qi, MM; Zhong, H; Cheng, ZY; Chen, SJ; Xiao, H; Shang, J; Chen, L; Sun, JB

Chen, L; Sun, JB (通讯作者),China Pharmaceut Univ, Sch Tradit Chinese Pharm, State Key Lab Nat Med, Nanjing 211198, Peoples R China.

JOURNAL OF MEDICINAL CHEMISTRY, 2023; 66 (13): 9184

Abstract

Activating Nrf2 through inhibitingKeap1 has been proven to alleviateoxidative stress and related diseases, including nonalcoholic fattyliver disease (......

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