Identification of patient-specific CD4+ and CD8+ T cell neoantigens through HLA-unbiased genetic screens

Cattaneo, CM; Battaglia, T; Urbanus, J; Moravec, Z; Voogd, R; de Groot, R; Hartemink, KJ; Haanen, JBAG; Voest, EE; Schumacher, TN; Scheper, W

Voest, EE; Schumacher, TN; Scheper, W (通讯作者),Netherlands Canc Inst, Dept Mol Oncol & Immunol, Amsterdam, Netherlands.;Voest, EE; Schumacher, TN (通讯作者),Oncode Inst, Utrecht, Netherlands.;Schumacher, TN (通讯作者),Leiden Univ, Med Ctr, Dept Hematol, Leiden, Netherlands.;Voest, EE (通讯作者),Netherlands Canc Inst, Dept Med Oncol, Amsterdam, Netherlands.

NATURE BIOTECHNOLOGY, 2023; 41 (6): 783

Abstract

Cancer neoantigens that arise from tumor mutations are drivers of tumor-specific T cell responses, but identification of T cell-recognized neoantigens......

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