Imbalance between nitric oxide and superoxide anion induced by uncoupled nitric oxide synthase contributes to human melanoma development

Goncalves, DA; Xisto, R; Goncalves, JD; da Silva, DB; Soares, JPM; Icimoto, MY; Sant'Anna, C; Gimenez, M; de Angelis, R; Llesuy, S; Fernandes, DC; Laurindo, F; Jasiulionis, MG; de Melo, FHM

de Melo, FHM (reprint author), Santa Casa Sao Paulo Sch Med Sci, Dept Physiol Sci, Sao Paulo, Brazil.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2019; 115 ():

Abstract

Melanoma is the most aggressive type of cutaneous tumors due to its metastatic potential and high mortality. Increased levels of reactive oxygen speci......

Full Text Link