Cyanocobalamin prevents cardiomyopathy in type 1 diabetes by modulating oxidative stress and DNMT-SOCS1/3-IGF-1 signaling

Kakoki, M; Ramanathan, PV; Hagaman, JR; Grant, R; Wilder, JC; Taylor, JM; Charles Jennette, J; Smithies, O; Maeda-Smithies, N

Kakoki, M (corresponding author), Univ N Carolina, Dept Pathol & Lab Med, Chapel Hill, NC 27515 USA.

COMMUNICATIONS BIOLOGY, 2021; 4 (1):

Abstract

Patients with long-standing diabetes have a high risk for cardiac complications that is exacerbated by increased reactive oxygen species (ROS) product......

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