Low HOX gene expression in PML-RAR-positive leukemia results from suppressed histone demethylation

Rejlova, K; Musilova, A; Kramarzova, KS; Zaliova, M; Fiser, K; Alberich-Jorda, M; Trka, J; Starkova, J

Starkova, J (reprint author), Charles Univ Prague, Fac Med 2, Dept Pediat Hematol & Oncol, V Uvalu 84, Prague, Czech Republic.

EPIGENETICS, 2018; 13 (1): 73

Abstract

Homeobox (HOX) genes are frequently dysregulated in leukemia. Previous studies have shown that aberrant HOX gene expression accompanies leukemogenesis......

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