Identification of Trovafloxacin, Ozanimod, and Ozenoxacin as Potent c-Myc G-quadruplex Stabilizers to Suppress c-Myc Transcription and Myeloma Growth

Zhang, JY; Wang, T; Geng, XJ; Liu, LL; Gao, J

Gao, J (通讯作者),Xuzhou Med Univ, Jiangsu Key Lab New Drug Res & Clin Pharm, Xuzhou 221004, Jiangsu, Peoples R China.

MOLECULAR INFORMATICS, 2022; 41 (10):

Abstract

c-Myc is a major oncogene that is estimated to result in almost all human cancers and the c-Myc downregulation has become an attractive strategy for c......

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