Extracellular HMGB1 augments macrophage inflammation by facilitating the endosomal accumulation of ALD-DNA via TLR2/4-mediated endocytosis

Lu, JC; Yue, Y; Xiong, SD

Yue, Y; Xiong, SD (corresponding author), Soochow Univ, Inst Biol, Suzhou 215123, Peoples R China.; Yue, Y; Xiong, SD (corresponding author), Soochow Univ, Inst Med Sci, Suzhou 215123, Peoples R China.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2021; 1867 (10):

Abstract

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with unclear pathogenesis. We previously reported that syngenetic, activated lympho......

Full Text Link