A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth

Ong, YT; Andrade, J; Armbruster, M; Shi, CY; Castro, M; Costa, ASH; Sugino, T; Eelen, G; Zimmermann, B; Wilhelm, K; Lim, J; Watanabe, S; Guenther, S; Schneider, A; Zanconato, F; Kaulich, M; Pan, DJ; Braun, T; Gerhardt, H; Efeyan, A; Carmeliet, P; Piccolo, S; Grosso, AR; Potente, M

Potente, M (通讯作者),Max Planck Inst Heart & Lung Res, Angiogenesis & Metab Lab, Bad Nauheim, Germany.;Potente, M (通讯作者),Charite Univ Med Berlin, Berlin Inst Hlth, Berlin, Germany.;Potente, M (通讯作者),Max Delbruck Ctr Mol Med Helmholtz Assoc, Berlin, Germany.;Potente, M (通讯作者),DZHK German Ctr Cardiovasc Res, Partner Site Berlin, Berlin, Germany.

NATURE METABOLISM, 2022; 4 (6): 672

Abstract

Ong et al. report how YAP/TAZ and mTORC1 signalling intersect in endothelial cells to regulate nutrient acquisition and vascular growth. Angiogenesis,......

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