Covalent CDK7 Inhibitor THZ1 Inhibits Myogenic Differentiation

Ma, XQ; Kuang, XL; Xia, Q; Huang, ZX; Fan, YT; Ning, J; Wen, JJ; Zhang, H; Yan, JH; Zhang, QJ; Shen, HX; Long, CD

Shen, HX; Long, CD (reprint author), Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, 54 Xianlie Rd, Guangzhou 510060, Guangdong, Peoples R China.

JOURNAL OF CANCER, 2018; 9 (17): 3149

Abstract

Covalent CDK7 inhibitor THZ1 is a newly discovered anti-tumor drug.THZ1 affects the function of transcription factor TFIIH by inhibiting CDK7, which i......

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