DKK1 drives immune suppressive phenotypes in intrahepatic cholangiocarcinoma and can be targeted with anti-DKK1 therapeutic DKN-01

Jarman, EJ; Horcas-Lopez, M; Waddell, SH; MacMaster, S; Gournopanos, K; Soong, DYH; Musialik, K; Tsokkou, P; Ng, ME; Cambridge, WA; Wilson, DH; Kagey, MH; Newman, W; Pollard, JW; Boulter, L

Jarman, EJ; Boulter, L (通讯作者),Univ Edinburgh, Inst Genet & Canc, MRC Human Genet Unit, Edinburgh EH4 2XU, Midlothian, Scotland.

LIVER INTERNATIONAL, 2023; 43 (1): 208

Abstract

Background and aims Dickkopf-1 (DKK1) is associated with poor prognosis in intrahepatic cholangiocarcinoma (iCCA), but the mechanisms behind this are ......

Full Text Link