Power of integrating PBPK with PBBM (PBPK-BM): a single model predicting food effect, gender impact, drug-drug interactions and bioequivalence in fasting & fed conditions

Boddu, R; Kollipara, S; Vijaywargi, G; Ahmed, T

Ahmed, T (通讯作者),Dr Reddys Labs Ltd, Integrated Prod Dev Org IPDO, Global Clin Management, Biopharmaceut Grp, Hyderabad 500090, India.

XENOBIOTICA, 2023; 53 (4): 260

Abstract

Over the past few years, PBPK and PBBM modelling have proven their significance in drug development. PBPK modelling is traditionally used to predict d......

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