CD28 Autonomous Signaling Orchestrates IL-22 Expression and IL-22-Regulated Epithelial Barrier Functions in Human T Lymphocytes

Kunkl, M; Amormino, C; Frascolla, S; Sambucci, M; De Bardi, M; Caristi, S; Arcieri, S; Battistini, L; Tuosto, L

Tuosto, L (corresponding author), Sapienza Univ, Dept Biol & Biotechnol Charles Darwin, Rome, Italy.; Tuosto, L (corresponding author), Sapienza Univ, Ist Pasteur Italia, Fdn Cenci Bolognetti, Rome, Italy.

FRONTIERS IN IMMUNOLOGY, 2020; 11 ():

Abstract

IL-22 is a member of the IL-10 cytokine family involved in host protection against extracellular pathogens, by promoting epithelial cell regeneration ......

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