The ruthenium complex assists in nuclear targeting and selective killing of tumor cells

Lu, Y; Zhu, D; Chan, LJ; Hu, B; Tuohan, M; Li, L; Wang, W; Wang, YJ

Wang, YJ (通讯作者)，Capital Med Univ, Coll Pharmaceut Sci, Dept Med Chem, Beijing 100069, Peoples R China.;Wang, YJ (通讯作者)，Capital Med Univ, Engn Res Ctr Endogenous Prophylact, Beijing Area Major Lab Peptide & Small Mol Drugs, Beijing Lab Biomed Mat,Minist Educ China,Beijing L, Beijing 100069, Peoples R China.;Wang, W (通讯作者)，Univ Bergen, Ctr Pharm, POB 7803, N-5020 Bergen, Norway.;Wang, W (通讯作者)，Univ Bergen, Dept Chem, POB 7803, N-5020 Bergen, Norway.

NANOSCALE, 2023; 15 (27): 11529

Abstract

In clinical studies, the toxicity of platinum-based antitumor drugs limits their use. DNA is the most widely studied target of metal-based complexes. ......

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