The inhibitory receptor Tim-3 fails to suppress IFN-gamma production via the NFAT pathway in NK-cell, unlike that in CD4(+) T cells

Yu, XW; Lang, B; Chen, X; Tian, Y; Qian, S; Zhang, ZN; Fu, YJ; Xu, JJ; Han, XX; Ding, HB; Jiang, YJ

Jiang, YJ (corresponding author), China Med Univ, NHC Key Lab AIDS Immunol, Natl Clin Res Ctr Lab Med, Affiliated Hosp 1, 155 Nanjing North St, Shenyang 110001, Liaoning, Peoples R China.; Jiang, YJ (corresponding author), Chinese Acad Med Sci, Key Lab AIDS Immunol, Shenyang 110001, Peoples R China.

BMC IMMUNOLOGY, 2021; 22 (1):

Abstract

Background T cell immunoglobulin and mucin domain-containing-3 (Tim-3) is a negative regulator expressed on T cells, and is also expressed on natural ......

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