Generation of a host cell line containing a MAR-rich landing pad for site-specific integration and expression of transgenes

Oliviero, C; Hinz, SC; Bogen, JP; Kornmann, H; Hock, B; Kolmar, H; Hagens, G

Hagens, G (通讯作者)，Haute Ecole Ingn HES SO Valais Wallis, Inst Life Technol, Sion, Switzerland.

BIOTECHNOLOGY PROGRESS, 2022; 38 (4):

Abstract

In recent years, targeted gene integration (TI) has been introduced as a strategy for the generation of recombinant mammalian cell lines for the produ......

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