Virtual Screening and Biological Activity Evaluation of New Potent Inhibitors Targeting LRRK2 Kinase Domain-MedSci.cn

Virtual Screening and Biological Activity Evaluation of New Potent Inhibitors Targeting LRRK2 Kinase Domain

Tan, SY; Gong, XQ; Liu, HX; Yao, XJ

Yao, XJ (corresponding author), Lanzhou Univ, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China.; Liu, HX (corresponding author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.

ACS CHEMICAL NEUROSCIENCE, 2021; 12 (17): 3214

Abstract

Leucine rich repeat kinase 2 (LRRK2) has been reported in the pathogenesis of Parkinson's disease (PD). Inhibition of LRRK2 kinase activity is a thera......

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