Development of a Macrophage-Based ADCC Assay

Uccellini, MB; Aslam, S; Liu, STH; Alam, F; Garcia-Sastre, A

Garcia-Sastre, A (corresponding author), Icahn Sch Med Mt Sinai, Dept Microbiol, New York, NY 10029 USA.; Garcia-Sastre, A (corresponding author), Icahn Sch Med Mt Sinai, Global Hlth & Emerging Pathogens Inst, New York, NY 10029 USA.; Garcia-Sastre, A (corresponding author), Icahn Sch Med Mt Sinai, Div Infect Dis, Dept Med, New York, NY 10029 USA.; Garcia-Sastre, A (corresponding author), Icahn Sch Med Mt Sinai, Tisch Canc Inst, New York, NY 10029 USA.

VACCINES, 2021; 9 (6):

Abstract

Fc-dependent effector functions are an important determinant of the in vivo potency of therapeutic antibodies. Effector function is determined by the ......

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