The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing

Ishihara, J; Ishihara, A; Starke, RD; Peghaire, CR; Smith, KE; McKinnon, TAJ; Tabata, Y; Sasaki, K; White, MJV; Fukunaga, K; Laffan, MA; Lutolf, MP; Randi, AM; Hubbell, JA

Hubbell, JA (reprint author), Univ Chicago, Inst Mol Engn, Chicago, IL 60637 USA.; Randi, AM (reprint author), Imperial Coll London, Natl Heart & Lung Inst, Vasc Sci, Hammersmith Campus, London W12 ONN, England.

BLOOD, 2019; 133 (24): 2559

Abstract

During wound healing, the distribution, availability, and signaling of growth factors (GFs) are orchestrated by their binding to extracellular matrix ......

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