Structure of UBE2K-Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension

Nakasone, MA; Majorek, KA; Gabrielsen, M; Sibbet, GJ; Smith, BO; Huang, DT

Huang, DT (通讯作者)，Canc Res UK Beatson Inst, Glasgow, Lanark, Scotland.;Huang, DT (通讯作者)，Univ Glasgow, Inst Canc Sci, Glasgow, Lanark, Scotland.

NATURE CHEMICAL BIOLOGY, 2022; 18 (4): 422

Abstract

Ubiquitin (Ub) chain types govern distinct biological processes. K48-linked polyUb chains target substrates for proteasomal degradation, but the mecha......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索