Anti-tumour effects of a macrolide analog F806 in oesophageal squamous cell carcinoma cells by targeting and promoting GLUT1 autolysosomal degradation

Li, X; Li, LY; Wu, XD; Wen, B; Lin, W; Cao, YF; Xie, L; Zhang, HF; Dong, G; Li, EM; Xu, LY; Cheng, YW

Xu, LY; Cheng, YW (通讯作者),Shantou Univ Med Coll, Dept Biochem & Mol Biol, Key Lab Mol Biol High Canc Incidence Coastal Chao, Shantou 515041, Guangdong, Peoples R China.

FEBS JOURNAL, 2022; 289 (21): 6782

Abstract

Cancer cells are characterized by altered energetic metabolism with increasing glucose uptake. F806, a 16-membered macrodiolide analogue, has anti-tum......

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