Histidine Metabolic Pathway Contributes to Clozapine-Induced Sialorrhea Based on Nontargeted Metabolomics

Zhang, K; Wu, SW; Wang, YT; Zhou, YF; Guo, JX; Xiao, AX; Ye, JR; Wu, BF; Li, SY; Zhu, FJ; Li, ZZ; Yu, L

Yu, L (通讯作者)，Guangzhou Med Univ, Affiliated Brain Hosp, Dept Tradit Chinese Med, Guangzhou, Peoples R China.;Li, ZZ (通讯作者)，Guangzhou Med Univ, Affiliated Brain Hosp, Dept Psychiat, Guangzhou, Peoples R China.;Li, ZZ (通讯作者)，Guangdong Engn Technol Res Ctr Translat Med Mental, Guangzhou, Peoples R China.;Yu, L (通讯作者)，Guangzhou Med Univ, Affiliated Tradit Chinese Med Hosp, Guangzhou, Peoples R China.

NEUROPSYCHOBIOLOGY, 2023; 82 (5): 271

Abstract

Introduction: Clozapine-induced sialorrhea (CIS) is one of the most common side effects of clozapine use, while the mechanism remains unclear. Methods......

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