Intestinal-specific Hdac3 deletion increases susceptibility to colitis and small intestinal tumor development in mice fed a high-fat diet

Ng, I; Luk, IY; Nightingale, R; Reehorst, CM; Dávalos-Salas, M; Jenkins, LJ; Fong, C; Williams, DS; Watt, MJ; Dhillon, AS; Mariadason, JM

Mariadason, JM (通讯作者)，Olivia Newton John Canc Res Inst, Melbourne, Vic, Australia.;Mariadason, JM (通讯作者)，La Trobe Univ, Sch Canc Med, Melbourne, Vic, Australia.;Mariadason, JM (通讯作者)，Univ Melbourne, Dept Med, Melbourne, Vic, Australia.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2023; 325 (6): G508

Abstract

High-fat (HF) diets (HFDs) and inflammation are risk factors for colon cancer; however, the underlying mechanisms remain to be fully elucidated. The t......

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